>Auric at 13:11, 1 April 2021

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{{BLP sources|date=January 2008}}

{{Infobox scientist
|name = Anirvan Ghosh
|image = AnirvanGhosh2020.jpg
|caption = Anirvan Ghosh in Boston, 2020
|birth_date = 1964
|birth_place = [[Bloomington, Indiana|Bloomington]], [[Indiana]], [[United States]]
|death_date =
|death_place =
|residence = [[California]], [[United States]]
|nationality = [[United States|American]]
|field = [[Neuroscience]]
| workplaces =
| patrons =
| education =
| alma_mater = [[Caltech]], [[Stanford University]]
| thesis_title = 
| thesis_url = 
| thesis_year = 
| doctoral_advisor = [[Carla J. Shatz]]
| academic_advisors = [[Michael E. Greenberg]]
|work_institution = [[University of California San Diego]], [[Johns Hopkins School of Medicine]], [[Harvard Medical School]], [[Stanford University]], [[California Institute of Technology]]
|prizes =
|religion =
|footnotes =
}}

'''Anirvan Ghosh''' ({{lang-bn|অনির্বাণ ঘোষ}}) is an American neuroscientist and Biotech executive.<ref name="Biosketch">{{cite web | url=http://ghoshlab.org/downloads/Ghosh_biosketch_12-15-10.pdf | title=Biosketch of Anirvan Ghosh 12-15-10 | publisher=The Ghosh Lab | accessdate=December 12, 2017}}</ref> His [[research]] has contributed to our understanding of the molecular mechanisms that regulate development and function of the [[mammalian]] [[brain]]. A major focus of his research has been to identify mechanisms that regulate neuronal connectivity and the effects of neuronal activity on [[brain development]].<ref>{{cite web
| last =
| first =
| authorlink =
| vauthors =
| title = Ghosh Lab Research Projects
| work = The Ghosh Lab
| publisher =UCSD
| date =
| url = http://ghoshlab.org/projects/index.html
| doi =
| accessdate = }}</ref> He served as the Global Head of Neuroscience Discovery at [[F. Hoffmann-La Roche]] from 2011 to 2016 and as founding CSO of E-Scape Bio from 2016-2017. He was the Head of Research and Early Development at [[Biogen]] from 2017-2020 and is currently the CEO of [[Unity Biotechnology]].<ref name="europeanpharmaceuticalreview.com">{{cite web|url=http://www.europeanpharmaceuticalreview.com/5717/news/industry-news/anirvan-ghosh-named-head-of-discovery-for-roches-cns-discovery-translational-area/|title=Anirvan Ghosh named Head of Discovery for Roche's CNS|website=European Pharmaceutical Review| date =21 February 2011|accessdate=11 December 2017}}</ref><ref name="biogen.com">{{cite web|url=http://newsroom.biogen.com/press-release/corporate/biogen-appoints-anirvan-ghosh-senior-vice-president-research-and-early-devel|title=Biogen Appoints Anirvan Ghosh Senior Vice President, Research and Early Development|website=Biogen Media|date=March 16, 2017|accessdate=11 December 2017|archive-url=https://web.archive.org/web/20170619084241/http://newsroom.biogen.com/press-release/corporate/biogen-appoints-anirvan-ghosh-senior-vice-president-research-and-early-devel|archive-date=19 June 2017|url-status=dead}}</ref><ref name="unity biotechnology.com">{{cite web|url=http://ir.unitybiotechnology.com/news-releases/news-release-details/unity-biotechnology-appoints-anirvan-ghosh-phd-chief-executive|title=UNITY BIOTECHNOLOGY APPOINTS ANIRVAN GHOSH, PH.D. AS CHIEF EXECUTIVE OFFICER}}</ref>

==Biography==

Anirvan Ghosh was born in 1964 in [[Bloomington, Indiana|Bloomington]], [[Indiana]] and grew up in [[Kanpur]], [[India]]. After completing high school at Central School ([[Kendriya Vidyalaya]]) [[IIT Kanpur]], he moved to the U.S. to pursue his undergraduate education at the [[California Institute of Technology]]. He graduated with a [[B.S.]] with honors in [[Physics]] from [[Caltech]] in 1985. From 1985 to 1990 he was a graduate student in the Stanford University Neurosciences Graduate Program, where he worked on the role of subplate neurons in establishing cortical connections in the laboratory of [[Carla J. Shatz]]. He received his [[Ph.D.]] in [[Neurobiology]] from [[Stanford University]] in 1991. His postdoctoral training was with [[Michael E. Greenberg]] at [[Harvard Medical School]] where he worked on regulation of differentiation by extracellular signals and calcium regulation of [[BDNF]] expression. From 1995 to 2003 he was on the [[Faculty (university)|faculty]] in the Department of Neuroscience at the [[Johns Hopkins School of Medicine]].<ref name="Biosketch"/> While at Johns Hopkins he cloned CREST as a calcium-regulated transcription factor and showed that it plays a critical role in brain development.<ref>{{cite web
| last =
| first =
| authorlink =
| vauthors =
| title = Cloning of CREST
| work =[[ScienceDaily]]
| date =January 9, 2004
| url = https://www.sciencedaily.com/releases/2004/01/040109065327.htm
| doi =
| accessdate = }}</ref> In 2003 he moved to [[UCSD]] as the [[Stephen Kuffler]] [[Professor]] and served as Chair of Neurobiology in the Division of Biological Sciences. Ghosh served as the Global Head of Neuroscience Discovery at [[Hoffmann-La Roche|Roche]] from 2011-2016 <ref name="europeanpharmaceuticalreview.com"/> and as the Head of Research and Early Development at Biogen from 2017-2020.<ref name="biogen.com"/> Since 2020 he has served as CEO of UNITY Biotechnology, a company focused on developing therapies to slow, halt, or reverse diseases of aging.

==Awards==

*EJLB Foundation Scholar Research Award
*Damon Runyon Scholar Award
*Klingenstein Fellowship Award in Neuroscience
*[[Alfred P. Sloan]] Research Fellow
*Pew Scholar Award
*[[Society for Neuroscience]] Young Investigator Award
*Presidential Early Career Award for Scientists and Engineers ([[PECASE]])
*UCSD [[Revelle College]] Outstanding Faculty Award

==Major publications==
*Ghosh, A., A. Antonini, S.K. McConnell and C.J. Shatz (1990). Requirement for subplate neurons in the formation of thalamocortical connections. ''Nature'' 347: 179-181
*Ghosh, A. and C.J. Shatz (1992). Involvement of subplate neurons in the formation of ocular dominance columns. ''Science'' 255:1441-1443.
*Ghosh, A., J. Carnahan and M.E. Greenberg (1994). Requirement for BDNF in activity-dependent survival of cortical neurons. ''Science'' 263:1618-1623.
*Ghosh, A. and M.E. Greenberg (1995). Distinct roles for bFGF and NT3 in the regulation of cortical neurogenesis. ''Neuron'' 15:89-103.
*Polleux, F., R.J. Giger, D.D. Ginty, A.L. Kolodkin, and A. Ghosh (1998). Patterning of cortical efferent projections by semaphorin-neuropilin interactions. ''Science'' 282:1904-1906.
*Polleux, F., T. Morrow and A. Ghosh (2000). Semaphorin 3A is a chemoattractant for developing cortical dendrites. ''Nature'' 404:567-573.
*Aizawa, H., Hu, S-C, Bobb, K., Balakrishnan, K., Ince, G., Gurevich, I., Cowan, M., and A. Ghosh (2004). Dendrite development regulated by CREST, a calcium-regulated transcription activator. ''Science'' 303:197-202.
*Qiu, Z. and A. Ghosh (2008) A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression. ''Neuron'' 60:775-787.
*Sylwestrak, E and A. Ghosh (2012) Elfn1 regulates target-specific release probability at CA1-interneuron synapses. ''Science'' 338:536-540.

==References==
<references/>

== External links ==
*[https://archive.is/20121212080701/http://biology.ucsd.edu/faculty/ghosh.html Official page: Anirvan Ghosh, Professor of Biology, UCSD]
*[http://www.biology.ucsd.edu/labs/ghosh/ The Ghosh Lab]
*''[[Science Daily]]'': [https://www.sciencedaily.com/releases/2004/01/040109065327.htm Gene Essential For Development Of Normal Brain Connections Resulting From Sensory Input Discovered]
*[http://www.sciencemag.org/cgi/content/short/303/5655/197 ''Science'': Dendrite Development Regulated by CREST, a Calcium-Regulated Transcriptional Activator]
*[http://www.jhu.edu/~gazette/octdec97/dec1597/15ghosh.html Johns Hopkins University Gazette: Heads up! The Brain Behind The Acclaim, by Michael Purdy]
*[https://web.archive.org/web/20080928210513/http://www.elsevier.com/wps/find/bookdescription.cws_home/713893/description#description Fundamental Neuroscience, Elsevier]
*[https://web.archive.org/web/20110505222424/http://www.pewtrusts.org/our_work_detail.aspx?id=652 Directory of Pew Scholars]
*[https://web.archive.org/web/20170423061941/http://newsroom.biogen.com/press-release/corporate/biogen-appoints-anirvan-ghosh-senior-vice-president-research-and-early-devel BIOGEN press release]
*[http://ir.unitybiotechnology.com/news-releases/news-release-details/unity-biotechnology-appoints-anirvan-ghosh-phd-chief-executive UNITY BIOTECHNOLOGY press release]

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{{DEFAULTSORT:Ghosh, Anirvan}}
[[Category:1964 births]]
[[Category:Bengali scientists]]
[[Category:American people of Bengali descent]]
[[Category:American neuroscientists]]
[[Category:People from Kanpur]]
[[Category:California Institute of Technology alumni]]
[[Category:Stanford University alumni]]
[[Category:Harvard Medical School alumni]]
[[Category:Johns Hopkins University faculty]]
[[Category:University of California, San Diego faculty]]
[[Category:Living people]]
[[Category:Kendriya Vidyalaya alumni]]
[[Category:Bengali people]]
[[Category:American academics of Indian descent]]
[[Category:Scientists from California]]

Anirvan Ghosh - Revision history

>Auric at 13:11, 1 April 2021