Sera at 01:41, 29 January 2026

2026-01-29T01:41:49Z

New page

{{Short description|Indian structural biologist}}
{{Use dmy dates|date=March 2019}}
{{Use Indian English|date=March 2019}}
{{Infobox scientist
| name = Arun Kumar Shukla
| image =
| alt =
| caption =
| birth_date =
| birth_place = [[Kushinagar]], [[Uttar Pradesh]], India
| death_date =
| death_place =
| fields = {{ublist | [[Structural biology]] }}
| workplaces = {{ublist | [[Duke University]] | [[Indian Institute of Technology, Kanpur]] }}
| alma_mater = {{ublist|[[Jawaharlal Nehru University]] | [[Max Planck Institute of Biophysics|Max Planck Institute]]|[[Duke University]] | [[Stanford University]] }}
| doctoral_advisor = {{ublist|[[Hartmut Michel]] | [[Robert J. Lefkowitz]] | [[Brian Kobilka]]}}
| doctoral_students =
| known_for = Studies on [[G protein-coupled receptor]]
| awards = {{ublist| 2025 [[Fellow, TWAS]] in Biological Sciences | 2024 [[OPPI Scientist of the Year Award]] |2023  [[Infosys Prize]] in Life Sciences |2022 Fellow, [[Indian National Science Academy]] | 2021 [[Fellowship, Indian Academy of Sciences]] | 2021 [[Khosla National Award of IIT Roorkee]] | 2021 [[Fellowship, National Academy of Sciences]] | 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]]| 2019 [[Rajib Goyal Prize by Kurukshetra University]]| 2017 B. M. Birla Science Prize | 2016 [[National Academy of Sciences, India|NASI]]-Young Scientist Platinum Jubilee Award | 2017 EMBO Young Investigator Award | 2017/18 [[National Bioscience Award for Career Development|N-BIOS Prize]] | 2018 [[Indian Council for Medical Research|ICMR]] Shakuntala Amir Chand Prize | 2018 [[Central Drug Research Institute|CDRI]] Award}}
}}
'''Arun Kumar Shukla''' is an Indian structural biologist and the Joy-Gill Chair professor at the department of biological sciences and bioengineering at the [[Indian Institute of Technology, Kanpur]].<ref name="Arun K. Shukla IITK">{{Cite web |url=https://www.iitk.ac.in/bsbe/arun-k-shukla |title=Arun K. Shukla IITK |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}}</ref> Known for his studies on [[G protein-coupled receptor]], Shukla is a [[Wellcome Trust]]-[[Department of Biotechnology|DBT]] Intermediate Fellow and a recipient of the SwarnaJayanti Fellowship of the [[Department of Science and Technology (India)|Department of Science and Technology]].<ref name="List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18">{{Cite web |url=http://www.dst.gov.in/sites/default/files/Final-List-SwarnaJayanti-Fellows-2017-18.pdf |title=List of Awardees - SwarnaJayanti Fellowships Scheme – 2017-18 |date=2018-12-30 |website=Department of Science and Technology |access-date=2018-12-30}}</ref> The [[Department of Biotechnology]] of the Government of India awarded him the [[National Bioscience Award for Career Development]], one of the highest Indian science awards, for his contributions to biosciences, in 2017/18. He received the 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]] in [[Biological Science]].<ref name="sbprize">{{cite web |title=Shanti Swarup Bhatnagar Prize (SSB) for Science and Technology 2021 |url=https://ssbprize.gov.in/WriteReadData/LatestUpdates/202109260133259214500SSBPrize2021Website.pdf |website=sbprize.gov.in |publisher=[[Council of Scientific and Industrial Research]] |access-date=26 September 2021}}</ref> He was awarded the [https://www.infosysprize.org/laureates/2023/arun-shulka.html Infosys Prize 2023] in Life Sciences his outstanding contributions to the biology of G-protein coupled receptors (GPCRs).

== Biography ==
[[File:A building at IIT Kanpur.jpg|thumb|left|IIT Kanpur]]
Dr. Arun Kumar Shukla was born on 1 November 1981<ref>{{cite web |title=Arun Kumar Shukla Biography |url=https://nikhilbharat.com/arun-kumar-shukla-biography-in-hindi/ |website=Online Hindi world |date=27 November 2021}}</ref> in [[Kushinagar]] in the Indian state of [[Uttar Pradesh]],<ref name="Better pill">{{Cite web |url=https://www.telegraphindia.com/science-tech/better-pill/cid/1377263 |title=Better pill |date=2018-12-30 |website=www.telegraphindia.com |language=en |access-date=2018-12-30}}</ref> earned his master's degree in biotechnology from [[Jawaharlal Nehru University]] after which he did his doctoral studies under the guidance of [[Hartmut Michel]] (Nobel Laureate, 1988) of [[Max Planck Institute of Biophysics]].<ref name="Arun K. Shukla IITK" /> His post-doctoral work was with [[Robert J. Lefkowitz]] (Nobel Laureate, 2012) of [[Duke University]] and [[Brian Kobilka]] (Nobel Laureate, 2012) of [[Stanford University]] and he started his career at Duke University as an assistant professor at their department of medicine. Returning to India, he joined the [[Indian Institute of Technology, Kanpur]] (IITK) at the Department of Biological Sciences and Bioengineering (BSBE)<ref name="BSBE People">{{Cite web |url=https://www.iitk.ac.in/bsbe/people |title=BSBE People |date=2018-12-30 |website=www.iitk.ac.in |access-date=2018-12-30}}</ref> where he holds the position of a professor<ref name="Arun Shukla on Samviti">{{Cite web |url=https://samviti.com/profile/arun-shukla-NzA4 |title=Arun Shukla on Samviti |date=2018-12-30 |website=samviti.com |language=en |access-date=2018-12-30}}</ref> and heads the ''Laboratory of GPCR Biology''.<ref name="Principal Investigator - Laboratory of GPCR Biology">{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/curriculum-vitae |title=Principal Investigator - Laboratory of GPCR Biology |date=2018-12-30 |website=sites.google.com |access-date=2018-12-30}}</ref>

Shukla is known to have carried out extensive research on [[G protein-coupled receptor]] and his research is reported to have led to easier regulation of these receptors for better drug efficacy.<ref name="Drug discovery for GPCR signalling made easy by IIT Kanpur">{{Cite news |url=https://www.thehindu.com/sci-tech/Drug-discovery-for-GPCR-signalling-made-easy-by-IIT-Kanpur/article16973255.ece |title=Drug discovery for GPCR signalling made easy by IIT Kanpur |last=Prasad |first=R. |date=2017-01-01 |newspaper=The Hindu |language=en-IN |access-date=2018-12-30}}</ref> He led a team of IITK scientists who developed ''nanomachines'' which could be designed to ''selectively target signalling events inside living cells''.<ref name="IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells">{{Cite web |url=https://www.thehindubusinessline.com/news/science/iitkanpur-scientistled-team-designs-nanomachines-that-can-correct-anomalies-inside-living-cells/article9885557.ece |title=IIT-Kanpur scientist-led team designs nano-machines that can correct anomalies inside living cells |last=Jayan |first=T. V. |date=8 January 2018 |website=@businessline |language=en |access-date=2018-12-30}}</ref> The technique developed by them is in use with several drugs that are available in the market such as [[Telmisartan]], [[Olmesartan]], [[Fexofenadine]], [[Propranolol]], and [[Metoprolol]].<ref name="Better pill" /> He has published a number of articles and has contributed chapters to books published by others;<ref name="Research Publications - Laboratory of GPCR Biology">{{Cite web |url=https://sites.google.com/site/laboratoryofgpcrbiology/publica |title=Research Publications - Laboratory of GPCR Biology |date=2018-12-31 |website=sites.google.com |access-date=2018-12-31}}</ref>{{Refn|group=note|Please see ''Selected bibliography'' section}} [[Google Scholar]], an online repository of scientific articles has listed 75 of them.<ref name="Arun K. Shukla - Google Scholar Citations">{{Cite web |url=https://scholar.google.co.in/citations?user=xIgDSCwAAAAJ&hl=en |title=Arun K. Shukla - Google Scholar Citations |date=2018-12-31 |website=scholar.google.co.in |access-date=2018-12-31}}</ref>

== Awards and honours ==
Shukla received the [[Infosys Prize]] 2023 in Life Sciences, he was selected for this prestigious award by an eminent jury chaired by MIT Professor, [https://www.infosysprize.org/jury/life-sciences.html Mriganka Sur]. He received the 2021 [[Shanti Swarup Bhatnagar Prize for Science and Technology]] in [[Biological Science]].<ref name="sbprize"/> The [[Department of Biotechnology]] of the Government of India awarded him the [[National Bioscience Award for Career Development]], one of the highest Indian science awards, for his contributions to biosciences, in 2017/18.<ref name="Awardees of National Bioscience Awards for Career Development">{{Cite web |url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |title=Awardees of National Bioscience Awards for Career Development |date=2016 |publisher=Department of Biotechnology |access-date=2017-11-20 |archive-date=4 March 2018 |archive-url=https://web.archive.org/web/20180304191331/http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf |url-status=dead }}</ref> He has also received the B. M. Birla Science Prize (2017),<ref name="BM Birla Science Prize presented">{{Cite web |url=https://www.thehansindia.com/posts/index/Telangana/2018-01-29/BM-Birla-Science-Prize-presented/354957 |title=BM Birla Science Prize presented |date=2018-12-31 |website=www.thehansindia.com |access-date=2018-12-31}}</ref> NASI-Young Scientist Platinum Jubilee Award of the [[National Academy of Sciences, India]] (2016),<ref name="The National Academy of Sciences, India - Activities">{{Cite web |url=http://www.nasi.org.in/yspja.htm |title=The National Academy of Sciences, India - Activities |date=2018-12-31 |website=www.nasi.org.in |access-date=2018-12-31 |archive-date=9 January 2019 |archive-url=https://web.archive.org/web/20190109212436/http://www.nasi.org.in/yspja.htm |url-status=dead }}</ref> [[Central Drug Research Institute|CDRI]] Award (2018),<ref name="List of previous CDRI Awardees">{{Cite web |url=http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |title=List of previous CDRI Awardees |date=2018-12-31 |website=Central Drug Research Institute |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194121/http://www.cdri.res.in/pdf/CDRIAwardsNotification.pdf |archive-date=31 December 2018 |url-status=dead }}</ref> Shakuntala Amir Chand Prize of the [[Indian Council for Medical Research]] (2018)<ref name="Awards - Indian Council of Medical Research">{{Cite web |url=https://www.icmr.gov.in/awards |title=Awards - Indian Council of Medical Research |date=2018-12-31 |website=ICMR |access-date=2018-12-31 |archive-url=https://web.archive.org/web/20181231194130/https://www.icmr.gov.in/awards |archive-date=31 December 2018 |url-status=dead }}</ref><ref name="News Archive">{{Cite web |url=https://www.iitk.ac.in/dofa/news-archive |title=News Archive |last=Vishwas |date=2018-12-31 |website=www.iitk.ac.in |language=en-gb |access-date=2018-12-31}}</ref> and the EMBO Young Investigator Award (2017).<ref name="IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator.">{{Cite web |url=https://www.pinterest.com/pin/155514993366608507/ |title=IITK faculty Dr. Arun Shukla, Department of Biosciences & bioengineering has been selected as the EMBO Young Investigator |date=2018-12-30 |website=Pinterest |language=en |access-date=2018-12-30}}</ref> He was elected as a fellow of the [[Indian National Science Academy]] in 2022.<ref name="INSA :: Indian Fellows Elected">{{Cite web |title=INSA :: Indian Fellows Elected |url=https://www.insaindia.res.in/ref3.php |access-date=2022-10-22 |website=www.insaindia.res.in}}</ref> In 2022 and 2024, Shukla was a laureate of the [[Asian Scientist 100]] by the ''[[Asian Scientist]]''.

== Selected bibliography ==
* {{Cite journal |last1=Ghosh |first1=Eshan |last2=Nidhi |first2=Kumari |last3=Shukla |first3=Arun K. |date=2014 |title=SnapShot: GPCR-Ligand Interactions |journal=Cell |volume=159 |issue=7 |pages=1712–1712.e1 |doi=10.1016/j.cell.2014.12.008 |pmid=25525884 |issn=0092-8674|doi-access=free }}
* {{Cite journal |last1=Reiter |first1=Eric |last2=Ahn |first2=Seungkirl |last3=Shukla |first3=Arun K. |last4=Lefkowitz |first4=Robert J. |date=2012-01-11 |title=Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors |journal=Annual Review of Pharmacology and Toxicology |volume=52 |issue=1 |pages=179–197 |doi=10.1146/annurev.pharmtox.010909.105800 |issn=0362-1642 |pmc=3628752 |pmid=21942629}}
* {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Yates |first2=John R. |last3=Shenoy |first3=Sudha K. |last4=Chen |first4=Minyong |last5=Zhao |first5=Yang |last6=Shukla |first6=Arun K. |last7=McClatchy |first7=Daniel B. |last8=Xiao |first8=Kunhong |date=2007-07-17 |title=Functional specialization of β-arrestin interactions revealed by proteomic analysis |journal=Proceedings of the National Academy of Sciences |language=en |volume=104 |issue=29 |pages=12011–12016 |doi=10.1073/pnas.0704849104 |issn=1091-6490 |pmc=1913545 |pmid=17620599 |bibcode=2007PNAS..10412011X |doi-access=free }}
* {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Whalen |first2=Erin J. |last3=Muehlbauer |first3=Michael J. |last4=Chen |first4=J. Ruthie |last5=Lam |first5=Christopher M. |last6=DeWire |first6=Scott M. |last7=Violin |first7=Jonathan D. |last8=Kovacs |first8=Jeffrey J. |last9=Shukla |first9=Arun K. |date=2009-05-01 |title=β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice |journal=The Journal of Clinical Investigation |language=en |volume=119 |issue=5 |pages=1312–1321 |doi=10.1172/JCI36806 |issn=0021-9738 |pmc=2673863 |pmid=19349687}}
* {{Cite journal |last1=Lefkowitz |first1=Robert J. |last2=Gygi |first2=Steven P. |last3=Ma'ayan |first3=Avi |last4=Mizuno |first4=Kensaku |last5=Cheng |first5=Yishan |last6=Lin |first6=Yuan |last7=Zhao |first7=Shan |last8=Lachmann |first8=Alexander |last9=Hernandez |first9=Marylens |date=2010-08-24 |title=Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) |journal=Proceedings of the National Academy of Sciences |language=en |volume=107 |issue=34 |pages=15299–15304 |doi=10.1073/pnas.1008461107 |issn=1091-6490 |pmc=2930550 |pmid=20686112 |bibcode=2010PNAS..10715299X |doi-access=free }}

== See also ==
{{portal|India||Biology}}
* [[Cell signaling]]
* [[Arrestin]]
* [[Membrane proteins]]

== Notes ==
{{reflist|group=note|2}}

== References ==
{{reflist}}

== Further reading ==
* {{Cite journal |last=The |first=Company of Biologists |date=2017-02-15 |title=Cell scientist to watch – Arun Shukla |journal=J Cell Sci |language=en |volume=130 |issue=4 |pages=659–661 |doi=10.1242/jcs.201384 |issn=1477-9137 |doi-access=free }}
* {{Cite journal |last=Gewin |first=Virginia |date=2015-04-15 |title=Turning point: Arun Shukla |journal=Nature |language=en |volume=520 |issue=7547 |pages=397 |doi=10.1038/nj7547-397a |issn=0028-0836|doi-access=free }}

== External links ==
* {{Cite web |url=https://www.youtube.com/watch?v=2tJIEBO25AQ |title=Prof. Arun K Shukla @Department of Biological Sciences and Bioengineering |last=IIT KANPUR |website=[[YouTube]] |date=16 August 2017 |access-date=2018-12-30}}

{{N-BIOS Laureates 2010–2019}}
{{SSBPST recipients in Biological Science}}
{{authority control}}

{{DEFAULTSORT:Shukla, Arun Kumar}}
[[Category:Year of birth missing (living people)]]
[[Category:N-BIOS Prize recipients]]
[[Category:People from Kanpur]]
[[Category:Jawaharlal Nehru University alumni]]
[[Category:Max Planck Society alumni]]
[[Category:Duke University alumni]]
[[Category:Duke University School of Medicine faculty]]
[[Category:Stanford University alumni]]
[[Category:Academic staff of IIT Kanpur]]
[[Category:Indian biologists]]
[[Category:Living people]]

Arun Kumar Shukla - Revision history

Sera at 01:41, 29 January 2026