<?xml version="1.0"?>
<feed xmlns="http://www.w3.org/2005/Atom" xml:lang="en">
	<id>https://indianpedia.org/index.php?action=history&amp;feed=atom&amp;title=Dorairajan_Balasubramanian</id>
	<title>Dorairajan Balasubramanian - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://indianpedia.org/index.php?action=history&amp;feed=atom&amp;title=Dorairajan_Balasubramanian"/>
	<link rel="alternate" type="text/html" href="https://indianpedia.org/index.php?title=Dorairajan_Balasubramanian&amp;action=history"/>
	<updated>2026-08-01T02:31:33Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.45.4</generator>
	<entry>
		<id>https://indianpedia.org/index.php?title=Dorairajan_Balasubramanian&amp;diff=477020&amp;oldid=prev</id>
		<title>DenicePitcairn at 17:35, 7 November 2025</title>
		<link rel="alternate" type="text/html" href="https://indianpedia.org/index.php?title=Dorairajan_Balasubramanian&amp;diff=477020&amp;oldid=prev"/>
		<updated>2025-11-07T17:35:43Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{Short description|Indian biophysical chemist and ocular biochemist}}&lt;br /&gt;
{{Use dmy dates|date=August 2020}}&lt;br /&gt;
{{Use Indian English|date=August 2020}}&lt;br /&gt;
{{Infobox person&lt;br /&gt;
| name               = Dorairajan Balasubramanian&lt;br /&gt;
| image              = &lt;br /&gt;
| imagesize          = &lt;br /&gt;
| caption            = &lt;br /&gt;
| birth_date         = {{birth date and age|1939|8|28|df=yes}}&lt;br /&gt;
| birth_place        = [[Tamil Nadu]], India&lt;br /&gt;
| death_date         = &lt;br /&gt;
| death_place        = &lt;br /&gt;
| restingplace       = &lt;br /&gt;
| restingplacecoordinates = &lt;br /&gt;
| occupation         = Biophysical chemist&lt;br /&gt;
| yearsactive        = since 1965&lt;br /&gt;
| known for          = [[Ocular]] [[biochemistry]]&lt;br /&gt;
| spouse             = Shakti&lt;br /&gt;
| children           = 2&lt;br /&gt;
| alma_mater         = [[BITS, Pilani]]&lt;br /&gt;
| website            = {{url|http://www.leopoldina.org/fileadmin/redaktion/Mitglieder/CV_Balasubramanian_Dorairajan_EN.pdf|Profile on Academy of Sciences Leopoldina}}&lt;br /&gt;
| awards             = {{Plainlist|[[Padma Shri]]&amp;lt;br /&amp;gt;&lt;br /&gt;
[[National Order of Merit (France)]]&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Shanti Swarup Bhatnagar Prize]]&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Third World Academy of Science]] Award&amp;lt;br /&amp;gt;&lt;br /&gt;
Khwarizmi Award&amp;lt;br /&amp;gt;&lt;br /&gt;
[[UNESCO]] [[Kalinga Prize]]&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Indian National Science Academy|INSA]] Indira Gandhi Prize&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Department of Science and Technology (India)|DST]] National Prize&amp;lt;br /&amp;gt;&lt;br /&gt;
Goyal Prize&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Indian National Science Academy|INSA]] J. C. Bose Medal&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Om Prakash Bhasin Award]]&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Indian Association for the Cultivation of Science|IACS]] Dr. Mahendra Lal Sircar Prize&amp;lt;br /&amp;gt;&lt;br /&gt;
Fukui Award&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Ranbaxy]] Research Award&amp;lt;br /&amp;gt;&lt;br /&gt;
SBCI Sarma Memorial Award&amp;lt;br /&amp;gt;&lt;br /&gt;
[[FICCI]] Award&amp;lt;br /&amp;gt;&lt;br /&gt;
[[Indian Council of Medical Research|ICMR]] M. O. T. Iyengar Award&amp;lt;br /&amp;gt;&lt;br /&gt;
Rev. Fr. L. M. Yeddanapalli Memorial Award}}&lt;br /&gt;
}}&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Dorairajan Balasubramanian&amp;#039;&amp;#039;&amp;#039;, popularly known as &amp;#039;&amp;#039;&amp;#039;Professor Balu&amp;#039;&amp;#039;&amp;#039;, is an Indian biophysical chemist&amp;lt;ref name=&amp;quot;TPB Research&amp;quot;&amp;gt;{{cite web | url=http://tributetoprofbalasubramanian.org/Research%20Contribution.aspx | title=TPB Research | publisher=TPB | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20150128112849/http://tributetoprofbalasubramanian.org/Research%20Contribution.aspx | archive-date=28 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt; and [[ocular]] [[biochemist]].&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot;&amp;gt;{{cite web | url=http://www.ever.be/download_file.php?id=58 | title=EVER Profile | publisher=EVER | date=2015 | access-date=22 January 2015}}&amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot;&amp;gt;{{cite web | url=http://tributetoprofbalasubramanian.org/Biography.aspx | title=TPB | publisher=TPB | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20150128113542/http://tributetoprofbalasubramanian.org/Biography.aspx | archive-date=28 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot;&amp;gt;{{cite web | url=http://www.bitsaa.org/news/71703/Profile-of-Professor-Dorairajan-Balasubramanian.htm | title=Bitsaa | publisher=Bitsaa | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20150128132002/http://www.bitsaa.org/news/71703/Profile-of-Professor-Dorairajan-Balasubramanian.htm | archive-date=28 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot;&amp;gt;{{cite web | url=http://insaindia.org.in/detail.php?id=N88-0984 | archive-url=https://web.archive.org/web/20160813001550/http://insaindia.org.in/detail.php?id=N88-0984 | url-status=usurped | archive-date=13 August 2016 | title=INSA | publisher=INSA | date=2015 | access-date=22 January 2015}}&amp;lt;/ref&amp;gt; He is a former President of [[Indian Academy of Sciences]]&amp;lt;ref name=&amp;quot;Prof. Dorairajan Balasubramanian-President 2007-09 &amp;quot;&amp;gt;{{cite web | url=https://www.youtube.com/watch?v=lcYn4KXT9PU | title=Prof. Dorairajan Balasubramanian-President 2007-09 | publisher=Indian Academy of Sciences | website=YouTube video | date=6 November 2013 | access-date=22 January 2015}}&amp;lt;/ref&amp;gt; and a director of research at the Prof. Brien Holden Eye Research Centre of [[L. V. Prasad Eye Institute]], Hyderabad.&amp;lt;ref name=&amp;quot;Israel Asia Centre Interview&amp;quot;&amp;gt;{{cite web | url=http://www.israelasiacenter.org/#/qa-balasubramanian/4541607121 | title=Israel Asia Centre Interview | publisher=Israel Asia Centre | date=June 2010 | access-date=22 January 2015}}&amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot;&amp;gt;{{cite web | url=http://www.leopoldina.org/fileadmin/redaktion/Mitglieder/CV_Balasubramanian_Dorairajan_EN.pdf | title=Leopoldina | publisher=Nationale Akademie der Wissenschaften Leopoldina | date=2015 | access-date=22 January 2015}}&amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;LVPEI&amp;quot;&amp;gt;{{cite web | url=http://www.lvpei.org/key-people.php | title=LVPEI | publisher=LVPEI | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20150117020257/http://www.lvpei.org/key-people.php | archive-date=17 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt; A recipient of the [[National Order of Merit (France)]], Balasubramanian was honored by the [[Government of India]], in 2002, with the fourth highest [[Indian honours system|Indian civilian award]] of [[Padma Shri]].&amp;lt;ref name=&amp;quot;Padma Awards&amp;quot;&amp;gt;{{cite web |url=http://mha.nic.in/sites/upload_files/mha/files/LST-PDAWD-2013.pdf |title=Padma Awards |publisher=Padma Awards |date=2015 |access-date=11 November 2014 |url-status=dead |archive-url=https://web.archive.org/web/20151015193758/http://mha.nic.in/sites/upload_files/mha/files/LST-PDAWD-2013.pdf |archive-date=15 October 2015 }}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Biography==&lt;br /&gt;
Dorairajan Balasubramanian was born on 28 August 1939&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; in the South Indian state of [[Tamil Nadu]].&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; He graduated in Chemistry (BSc) from [[Madras University]] in 1957 and secured his master&amp;#039;s degree (MSc) in Chemistry with first rank&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; in 1959 from [[BITS, Pilani]].&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; He moved to the United States in 1960 for researching for his doctoral studies and completed it in 1965 to obtain PhD&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; in biophysical chemistry from [[Columbia University]].&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; He continued in the United States for his post doctoral research as a [[Jane Coffin Childs Memorial Fund for Medical Research|Jane Coffin Childs Fund Fellow]] at the [[University of Minnesota Medical School]] till 1966.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Balasubramanian returned to India in 1966 and joined the [[Indian Institute of Technology, Kanpur]]&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; as a lecturer where he rose in ranks over the years to become an assistant professor and a professor.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; In 1977, he was appointed as the professor and dean of the School of Chemistry at the [[University of Hyderabad]]&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;LVPEI&amp;quot; /&amp;gt; where he worked till 1982&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; when he took up the post of the deputy director of the [[Centre for Cellular and Molecular Biology]].&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; He retired from the institution as its director&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; in 1998 and moved to [[L. V. Prasad Eye Institute]] where he is the director of research of Prof. Brien Holden Eye Research Centre.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;LVPEI&amp;quot; /&amp;gt; He also serves as the visiting professor at the [[University of New South Wales]], Sydney and as the adjunct professor of [[Birla Institute of Technology and Science]], Pilani, India.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Balasubramanian is married to Shakti who is associated with [[ETV Network|ETV]] as a producer and the couple has two daughters.&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; The elder daughter, Katyayani is a research analyst and the younger one, Akhila works as a public health professional.&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; The family lives in Hyderabad.&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Positions==&lt;br /&gt;
Balasubramanian is a visiting scientist at the [[National Eye Institute]], [[Bethesda, Maryland|Bethesda]] and is a senior Fellow of ophthalmology at the [[University of Melbourne]].&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt; He is the chairman of the &amp;#039;&amp;#039;Task Force on Stem Cell Research&amp;#039;&amp;#039; set up by the [[Department of Biotechnology]] of the [[Government of India]].&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; He is a former president of the [[Indian Academy of Sciences]] (2007-2010)&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; and is the incumbent the chairman of the Biotechnology Advisory Council of the [[Government of Andhra Pradesh]].&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt; A former secretary general of [[The World Academy of Sciences]],&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; he has served as the project coordinator of &amp;#039;&amp;#039;Translational Centre in Eye Diseases&amp;#039;&amp;#039; of [[Champalimaud Foundation]] (C-TRACER) and the &amp;#039;&amp;#039;Affordable Healthcare Project&amp;#039;&amp;#039; of the [[Wellcome Trust]] for finding solutions for the &amp;#039;&amp;#039;use of scaffolds for cultivating stem cells&amp;#039;&amp;#039;.&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; He is a former member of the &amp;#039;&amp;#039;International Human Rights Network of Academies and Scholarly Societies&amp;#039;&amp;#039;,&amp;lt;ref name=&amp;quot;NAP&amp;quot;&amp;gt;{{cite book | url=http://www.nap.edu/catalog/10706/international-human-rights-network-of-academies-and-scholarly-societies-proceedings | title=NAP | publisher=NAP | date=2015 | access-date=23 January 2015| doi=10.17226/10706 | isbn=978-0-309-56417-5 }}&amp;lt;/ref&amp;gt; the &amp;#039;&amp;#039;International Basic Sciences Panel&amp;#039;&amp;#039;&amp;lt;ref name=&amp;quot;IBSP&amp;quot;&amp;gt;{{cite web | url=http://portal.unesco.org/science/en/ev.php-URL_ID=1573&amp;amp;URL_DO=DO_TOPIC&amp;amp;URL_SECTION=201.html | title=IBSP | publisher=IBSP | date=2015 | access-date=23 January 2015}}&amp;lt;/ref&amp;gt; of [[UNESCO]] and the &amp;#039;&amp;#039;International Chapter Affiliate Committee of the Association for Research in Vision and Ophthalmology&amp;#039;&amp;#039; (ARVO),&amp;lt;ref name=&amp;quot;ARVO&amp;quot;&amp;gt;{{cite web | url=http://www.arvo.org/About_ARVO/Organization/Committees/International_Chapter_Affiliate_Committee/ | title=ARVO | publisher=ARVO | date=2015 | access-date=23 January 2015}}&amp;lt;/ref&amp;gt; United States.&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; He has also served as an editorial board member of several international journals.&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; He had also been appointed as one of the honorary advisory committee members for the International Conference on Genome Biology 2019 (ICGB&amp;#039;19) by the School of Biological Sciences of [[Madurai Kamaraj University]].&amp;lt;ref&amp;gt;{{cite web|url=https://www.readkong.com/page/school-of-biological-sciences-madurai-kamaraj-university-6308630|title= School of Biological Sciences Madurai Kamaraj University Madurai - 625021, India|publisher= School of Biological Sciences Madurai Kamaraj University|access-date=1 May 2010}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Legacy==&lt;br /&gt;
[[File:Cataract in human eye.png|thumb|left|Cataract in human eye]]&lt;br /&gt;
[[File:GINKGOBAUM-2.jpg|thumb|150px|Ginko tree]]&lt;br /&gt;
[[File:WithaniaFruit.jpg|thumb|150px|Withania]]&lt;br /&gt;
Balasubramanian started his research activities in 1965 focusing on the structure and functions of proteins and [[polypeptides]]&amp;lt;ref name=&amp;quot;Molecular Pathology of dityrosine Crosslinks in Protein&amp;quot;&amp;gt;{{Cite book | url=https://books.google.com/books?id=w7XLpRXg_cwC&amp;amp;q=Dorairajan+Balasubramanian&amp;amp;pg=PA27 | title=Molecular Pathology of dityrosine Crosslinks in Protein | publisher=Kluwer Academic Publishers | date=2002 | access-date=23 January 2015| isbn=9781402070853 }}&amp;lt;/ref&amp;gt; and worked on the thermodynamic analysis of their stability.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; The focus of his research changed in 1984/85 when he started to work on ocular science and concentrated on [[crystallins]] of eye lens and their function as an agent in keeping the lens transparent.&amp;lt;ref name=&amp;quot;ALTERATION OF DYNAMIC QUATERNARY STRUCTURE AND CALCIUM-BINDING ABILITY OF ß-CRYSTALLIN BY LIGHT&amp;quot;&amp;gt;{{cite journal | title=ALTERATION OF DYNAMIC QUATERNARY STRUCTURE AND CALCIUM-BINDING ABILITY OF ß-CRYSTALLIN BY LIGHT |author1=Yogendra Sharma |author2=A. Gopalakrishna |author3=D. Balasubramanian | journal=Photochemistry and Photobiology |date=January 2008  | volume=57 | issue=4 | pages=739–743 | doi=10.1111/j.1751-1097.1993.tb02947.x |pmid=8506401 |s2cid=35085602 }}&amp;lt;/ref&amp;gt; His research revealed how [[cataract]] is caused when crystallins are damaged photochemically, thereby leading to diminished lenticular transparency.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt; He argued that the oxidative stress on the lens induces &amp;#039;&amp;#039;covalent chemical changes in the constituent molecules&amp;#039;&amp;#039;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt; and these changes lead to cataract.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; He researched further on the subject to find out that, by supplementing [[antioxidants]] and cytoprotective substances, the progression of cataract can be slowed down.&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; These findings are known to have introduced a [[prophylactic]] approach to addressing the issue of cataract, which is reported to be the causal factor for 47.9 percent&amp;lt;ref name=&amp;quot;WHO&amp;quot;&amp;gt;{{cite web | url=https://www.who.int/blindness/causes/en/ | archive-url=https://web.archive.org/web/20060321053401/http://www.who.int/blindness/causes/en/ | url-status=dead | archive-date=21 March 2006 | title=WHO | publisher=WHO | date=2015 | access-date=23 January 2015}}&amp;lt;/ref&amp;gt; of the blindness in the world.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt; Further, he attempted to identify the cataractostatic agents and proposed the benefits of tea [[polyphenols]],&amp;lt;ref name=&amp;quot;Antioxidant Properties of Green and Black Tea, and their Potential Ability to Retard the Progression of Eye Lens Cataract&amp;quot;&amp;gt;{{cite journal | title=Antioxidant Properties of Green and Black Tea, and their Potential Ability to Retard the Progression of Eye Lens Cataract |author1=Geetha Thiagarajan |author2=Sushil Chandani |author3=C. Sivakama Sundan |author4=S. Harinarayana Rao |author5=Ajay V. Kulkarni |author6=D. Balasubrmanian |s2cid=23427305 | journal=Experimental Eye Research |date=September 2001  | volume=73 | issue=3 | pages=392–401 | doi=10.1006/exer.2001.1049| pmid=11520114 }}&amp;lt;/ref&amp;gt; [[Ginko Biloba]]&amp;lt;ref name=&amp;quot;Molecular and Cellular Assessment of Ginkgo Biloba Extract as a Possible Ophthalmic Drug&amp;quot;&amp;gt;{{cite journal | title=Molecular and Cellular Assessment of Ginkgo Biloba Extract as a Possible Ophthalmic Drug |author1=Geetha Thiagarajan |author2=Sushil Chandani |author3=Ayelet M. Samuni |author4=S. Harinarayana Rao |author5=Krish Chandrasekharan |author6=D. Balasubrmanian | journal=Experimental Eye Research |date=October 2002  | volume=75 | issue=4 | pages=421–430 | doi=10.1006/exer.2002.2035|pmid=12387790 }}&amp;lt;/ref&amp;gt; and [[Withania somnifera]] extracts.&amp;lt;ref name=&amp;quot;Approaches to relieve the burden of cataract blindness through natural antioxidants: use of Ashwagandha (Withania somnifera)&amp;quot;&amp;gt;{{cite journal | url=https://www.researchgate.net/publication/259558439 | title=Approaches to relieve the burden of cataract blindness through natural antioxidants: use of Ashwagandha (Withania somnifera) |author1=Geetha Natarajan |author2=Talla Venu |author3=D. Balasubramanian | journal=Current Science |date=October 2003  | volume=85 | issue=7 | pages=1065–1071}}&amp;lt;/ref&amp;gt; These substances contained antioxidants and cytoprotective compounds which slow down the progression of &amp;#039;&amp;#039;oxidative cataract&amp;#039;&amp;#039; and this was verified during experiments in animals.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&lt;br /&gt;
[[File:Eye disease simulation, glaucoma.jpg|thumb|left|Advanced vision loss from [[Glaucoma]].]]&lt;br /&gt;
&lt;br /&gt;
After the turn of the century, Balasubramanian and his colleagues started working on inherited eye diseases&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; and their [[molecular genetics]].&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; The group carried out research on diseases such as [[congenital glaucoma]]&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Identification of Novel Mutations Causing Familial Primary Congenital Glaucoma in Indian Pedigrees&amp;quot;&amp;gt;{{cite journal | url=http://www.iovs.org/content/43/5/1358.full.pdf+html | title=Identification of Novel Mutations Causing Familial Primary Congenital Glaucoma in Indian Pedigrees |author1=Shirly G. Panicker |author2=Aramati B. M. Reddy |author3=Anil K. Mandal |author4=Niyaz Ahmed |author5=Hampapathalu A. Nagarajaram |author6=Seyed E. Hasnain |author7=Dorairajan Balasubramanian | journal=Invest. Ophthalmol. Vis. Sci. |date=May 2002  | volume=43 | issue=5 | pages=1358–1366| pmid=11980847 }}&amp;lt;/ref&amp;gt; with a sampling set of over 400 families and this has helped in revealing 15 mutations in the &amp;#039;&amp;#039;gene CYP1B1&amp;#039;&amp;#039;, with mutation R368H being the most common one.&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Identification of Novel Mutations Causing Familial Primary Congenital Glaucoma in Indian Pedigrees&amp;quot; /&amp;gt; The research has also recorded the &amp;#039;&amp;#039;[[genotype]]–[[phenotype]] correlations&amp;#039;&amp;#039; and the structural changes occur in mutated protein&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Identification of Novel Mutations Causing Familial Primary Congenital Glaucoma in Indian Pedigrees&amp;quot; /&amp;gt; and these findings have assisted in clinical prediction of the disease and in early therapeutic intervention to avert blindness.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Balasubramanian is now working on [[stem cell biology]] and its use in restoring lost vision.&amp;lt;ref name=&amp;quot;Regenerative Medicine&amp;quot;&amp;gt;{{cite book | url=https://books.google.com/books?id=Xc1SHo0EHfYC&amp;amp;q=Dorairajan+Balasubramanian+books | title=Regenerative Medicine | publisher=Springer Science and Business Media | editor=Gustav Steinhoff  | year=2011 | pages=1056 | isbn=9789048190751}}&amp;lt;/ref&amp;gt; He and his group have been successful in isolating the adult stem cells found in the [[Limbus corneae|limbus]], around the [[cornea]], and culturing them on human [[amniotic membrane]].&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; These cultured stem cells were, later, used to produce [[corneal epithelia]] that can be stitched on to human eye. Clinical tests on 200 patients who lost eyesight due to chemical or fire burns returned significantly good results with vision restoration to 20/20 levels,&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; with or without subsequent [[corneal graft]]s or transplantation.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt; These tests are reported to be the &amp;#039;&amp;#039;largest successful human trial of adult stem cell therapy&amp;#039;&amp;#039; in the world.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Balasubramanian has published 6 books&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt; of which two books,&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt; one on chemistry and the other in [[biotechnology]], are prescribed text books for academic studies.&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;IISc&amp;quot;&amp;gt;{{cite web | url=http://www.iisc.ernet.in/centenary-conf/dbalasub.html | title=IISc | publisher=IISc | date=2015 | access-date=23 January 2015}}&amp;lt;/ref&amp;gt; He is credited with over 450 articles,&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; published in peer reviewed national and international journals&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Contributions&amp;quot;&amp;gt;{{cite web | url=http://tributetoprofbalasubramanian.org/Research%20Contribution.aspx | title=Contributions | publisher=TPB | date=2015 | access-date=23 January 2015 | archive-url=https://web.archive.org/web/20150128112849/http://tributetoprofbalasubramanian.org/Research%20Contribution.aspx | archive-date=28 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt; and [[Microsoft Academic Search]], an online repository of scientific articles, has listed 52 of them.&amp;lt;ref name=&amp;quot;Microsoft Academic Research&amp;quot;&amp;gt;{{cite web | url=http://65.54.113.26/Author/19548500/dorairajan-balasubramanian | title=Microsoft Academic Research | publisher=Microsoft Academic Research | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20160624041946/http://65.54.113.26/Author/19548500/dorairajan-balasubramanian | archive-date=24 June 2016 | url-status=dead }}&amp;lt;/ref&amp;gt; He has presented more than 170 scientific papers&amp;lt;ref name=&amp;quot;TPB Research&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; and has contributed in popularizing science by writing columns in leading newspapers such as [[The Hindu]] and [[The Times of India]] since 1980.&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;IISc&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Newspaper&amp;quot;&amp;gt;{{cite web | url=http://tributetoprofbalasubramanian.org/Popular%20Articles.aspx | title=Newspaper | publisher=TPB | date=2015 | access-date=23 January 2015 | archive-url=https://web.archive.org/web/20150128114551/http://tributetoprofbalasubramanian.org/Popular%20Articles.aspx | archive-date=28 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt; On the academic front, he has assisted 16 doctoral students in their PhD studies.&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; His efforts are also reported behind the establishment of a vaccine unit at the [[Centre for Cellular and Molecular Biology]] and in designing a quality improvement program for the [[Sericulture]] Laboratory of the state government.&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Awards and recognitions==&lt;br /&gt;
[[File:Padma Shri India IIIe Klasse.jpg|thumb|90px|Padma Shri India IIIe Klasse]]&lt;br /&gt;
[[File:Ordre national du merite chevalier FRANCE.jpg|thumb|90px|Chevalier de l&amp;#039;Ordre National du Mérite (France)]]&lt;br /&gt;
Dorairajan Balasubramanian, an honorary Professor of the [[Jawaharlal Nehru Centre for Advanced Scientific Research]], is an elected member of [[Indian National Science Academy]] (INSA), [[Indian Academy of Sciences]] (IAS), [[National Academy of Sciences, India]] (NASI), [[Third World Academy of Sciences]] (TWAS) and the [[American Association for the Advancement of Science]].&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot;&amp;gt;{{cite web | url=http://tributetoprofbalasubramanian.org/Awards%20and%20Honors.aspx | title=TPB Awards | publisher=TPB | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20150128131914/http://tributetoprofbalasubramanian.org/Awards%20and%20Honors.aspx | archive-date=28 January 2015 | url-status=dead }}&amp;lt;/ref&amp;gt; He is also a Fellow of the [[Academy of Sciences Leopoldina]],&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; Germany, Mauritian Academy of Sciences&amp;lt;ref name=&amp;quot;Leopoldina&amp;quot; /&amp;gt; and the International Molecular Biology Network.&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
He has delivered many award lectures in India and abroad. In 1985, he delivered the National Lecture of the [[University Grants Commission (India)|University Grants Commission]] and the next year, the Prof. K. Venkataraman Endowment Lecture.&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; K. S. G. Doss Memorial Lecture and the SERC National Lecture were delivered in 1991 followed by Pasteur Centenary Lecture, R. P. Mitra Memorial Lecture and the Platinum Jubilee Lecture of the [[Indian Science Congress Association]] in 1995. Some of the other award lectures given by Balasubramanian are:&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
{{Div col|colwidth=30em}}&lt;br /&gt;
* [[Madurai Kamaraj University]] Convocation Address&lt;br /&gt;
* Ranganathan Centre for Information Studies Annual Lecture&lt;br /&gt;
* J. C. Ray Memorial Oration Award&lt;br /&gt;
* [[C. V. Raman]] Lecture&lt;br /&gt;
* B. C. Guha Memorial Lecture&lt;br /&gt;
* Lily Pithavadian Endowment Lecture&lt;br /&gt;
* [[Banaras Hindu University|BHU]] Foundation Lecture&lt;br /&gt;
* TNAU-MFL Endowment Lecture&lt;br /&gt;
* Kumari L. A. Meera Memorial Lecture&lt;br /&gt;
* Prof. McBain Memorial Lecture&lt;br /&gt;
* [[Birbal Sahni Institute of Palaeobotany]] Foundation Day Lecture &lt;br /&gt;
* Jana Reddy Venkata Reddy Endowment Lecture&lt;br /&gt;
* Sri Venugopal Oration Medical Research Foundation Lecture&lt;br /&gt;
* Elite School of Optometry Convocation Address Foundation Day Lecture &lt;br /&gt;
* Dr. P. S. Murthy Memorial Lecture&lt;br /&gt;
* Dr. Ram Mohan Rao Oration&lt;br /&gt;
* Dr. K. Gopalakrishna Oration&lt;br /&gt;
{{div col end}}&lt;br /&gt;
&lt;br /&gt;
Balasubramanian received his first award, the Rev. Fr. L. M. Yeddanapalli Memorial Award and Medal of the [[Indian Chemical Society]] in 1977.&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; In 1981, he was awarded the [[Shanti Swarup Bhatnagar Prize]] in chemical science by the [[Council for Scientific and Industrial Research]].&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; The year 1983 brought him three awards, the SBCI Sarma Memorial Award, [[FICCI]] Award and the [[Indian Council of Medical Research|ICMR]] M. O. T. Iyengar Award.&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; He received the Ranbaxy Award in 1990,&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt; the Fukui Award of the National Foundation for Eye Research, United States, in 1991 and Dr. Mahendra Lal Sircar Prize from the [[Indian Association for the Cultivation of Science]] in 1994.&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The [[Third World Academy of Science]] honoured Balasubramanian with the [[TWAS Prize]] in 1995&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt; and [[Iranian Research Organization for Science and Technology]] (IROST) conferred the &amp;#039;&amp;#039;Khwarizmi Award of Iran&amp;#039;&amp;#039; on him in 1996.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; He received the [[Om Prakash Bhasin Award]] and the [[Kalinga Prize]] in 1997&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Kalinga Prize&amp;quot;&amp;gt;{{cite web | url=http://www.kalingafoundationtrust.com/website/kalinga-prize-for-the-popularization-of-science.htm | title=Kalinga Prize | publisher=Kalinga Foundation | date=2015 | access-date=22 January 2015}}&amp;lt;/ref&amp;gt; and the next year, he received Goyal Prize of the Goyal Research Foundation&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt; and J. C. Bose Medal of the [[Indian National Science Academy]] (INSA).&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; The [[Government of India]] honoured him with the civilian award of [[Padma Shri]] in 2002.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; The [[Government of France]] followed suit with the [[National Order of Merit (France)|Chevalier de l’Ordre National de Merite]], the same year.&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;Bitsaa&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt; He received a third award in 2002 from the [[Department of Science and Technology (India)|Department of Science and Technology]], the National Prize for Science Popularization.&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; He is also a recipient of the [[Indian National Science Academy|INSA]] Indira Gandhi Prize&amp;lt;ref name=&amp;quot;INSA&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;TPB Awards&amp;quot; /&amp;gt; and the Jawaharlal Nehru Centenary Award for Achievement in Science of the [[Indian Science Congress Association]] (ISCA).&amp;lt;ref name=&amp;quot;EVER Profile&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==See also==&lt;br /&gt;
{{Div col|colwidth=30em}}&lt;br /&gt;
* [[Crystallin]]&lt;br /&gt;
* [[Molecular genetics]]&lt;br /&gt;
* [[Stem cell biology]]&lt;br /&gt;
* [[Corneal epithelium]]&lt;br /&gt;
{{div col end}}&lt;br /&gt;
{{portal|India|Science}}&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
{{Reflist}}&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
* {{cite web | url=https://www.youtube.com/watch?v=lcYn4KXT9PU | title=Prof. Dorairajan Balasubramanian-President 2007-09 | publisher=Indian Academy of Sciences | website=YouTube video | date=6 November 2013 | access-date=22 January 2015}}&lt;br /&gt;
* {{cite web | url=http://www.israelasiacenter.org/#/qa-balasubramanian/4541607121 | title=Israel Asia Centre Interview | publisher=Israel Asia Centre | date=June 2010 | access-date=22 January 2015}}&lt;br /&gt;
* {{cite web | url=http://65.54.113.26/Author/19548500/dorairajan-balasubramanian | title=Microsoft Academic Research | publisher=Microsoft Academic Research | date=2015 | access-date=22 January 2015 | archive-url=https://web.archive.org/web/20160624041946/http://65.54.113.26/Author/19548500/dorairajan-balasubramanian | archive-date=24 June 2016 | url-status=dead }}&lt;br /&gt;
{{2000s Padma Shri Award Recipients in Science &amp;amp; Engineering}}&lt;br /&gt;
{{SSBPST recipients in Chemical Science}}&lt;br /&gt;
{{Shanti Swarup Bhatnagar Laureates of Tamil Nadu}}&lt;br /&gt;
{{Authority control}}&lt;br /&gt;
&lt;br /&gt;
{{DEFAULTSORT:Balasubramanian, Dorairajan}}&lt;br /&gt;
[[Category:Living people]]&lt;br /&gt;
[[Category:1939 births]]&lt;br /&gt;
[[Category:Scientists from Tamil Nadu]]&lt;br /&gt;
[[Category:Indian technology writers]]&lt;br /&gt;
[[Category:Recipients of the Shanti Swarup Bhatnagar Award in Chemical Science]]&lt;br /&gt;
[[Category:Recipients of the Shanti Swarup Bhatnagar Prize for Science and Technology]]&lt;br /&gt;
[[Category:Indian medical writers]]&lt;br /&gt;
[[Category:Recipients of the Padma Shri in science &amp;amp; engineering]]&lt;br /&gt;
[[Category:Fellows of the Indian National Science Academy]]&lt;br /&gt;
[[Category:Fellows of the Indian Academy of Sciences]]&lt;br /&gt;
[[Category:Fellows of the National Academy of Sciences, India]]&lt;br /&gt;
[[Category:Indian biochemists]]&lt;br /&gt;
[[Category:20th-century Indian chemists]]&lt;br /&gt;
[[Category:TWAS laureates]]&lt;br /&gt;
[[Category:Kalinga Prize recipients]]&lt;br /&gt;
[[Category:Associate fellows of the African Academy of Sciences]]&lt;br /&gt;
[[Category:Birla Institute of Technology and Science, Pilani alumni]]&lt;br /&gt;
[[Category:Om Prakash Bhasin Award recipients]]&lt;/div&gt;</summary>
		<author><name>DenicePitcairn</name></author>
	</entry>
</feed>