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{{Short description|Indian cell biologist and immunologist}}
{{Use Indian English|date=September 2017}}
{{Use dmy dates|date=September 2017}}
{{Infobox scientist
| name = Dr. Guru Prakash Dutta
| image =
| alt =
| caption =
| birth_date = {{birth date|df=yes|1933|11|19}}
| birth_place = India
| death_date = {{Death date and age|2021|4|25|1933|11|19|df=y}}
| death_place =
| residence =
| nationality = [[Indian nationality|Indian]]
| fields = [[Cell biology]]
| workplaces = {{ublist | [[Punjab University, Chandigarh, India|Punjab University]] | [[Central Drug Research Institute]] }}
| alma_mater = [[Punjab University, Chandigarh, India|Punjab University]]
| doctoral_advisor =
| doctoral_students =
| known_for = {{ublist | Experimental [[Protozoology]] | [[Immunology]] }}
| awards = 1976 [[Shanti Swarup Bhatnagar Prize]]
}}
'''Guru Prakash Dutta''' (19 November 1933 - 25 April 2021) was an Indian cell biologist and [[immunologist]], known for his contributions to the subjects of Experimental [[protozoology]] and [[Immunology]].<ref>{{cite web |title=Obituary |url=https://link.springer.com/article/10.1007/s12639-021-01406-w |publisher=Springer Link |access-date=12 August 2021}}</ref><ref name="Brief Profile of the Awardee">{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=449 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=19 September 2016}}</ref> His researches are reported to have assisted in the development of a number of [[anti-malarial]] drugs.<ref name="Indian Fellow - G. P. Dutta">{{cite web | url=http://insaindia.res.in/detail.php?id=N84-0230 | title=Indian Fellow - G. P. Dutta | publisher=Indian National Science Academy | date=2016 | access-date=21 September 2016}}</ref> He was an elected fellow of the [[Indian National Science Academy]], [[National Academy of Sciences, India]] and Indian Society of Parasitology. The [[Council of Scientific and Industrial Research]], the apex agency of the Government of India for scientific research, awarded him the [[Shanti Swarup Bhatnagar Prize for Science and Technology]], one of the highest Indian science awards, in 1976, for his contributions to biological sciences.<ref name="View Bhatnagar Awardees">{{cite web | url=http://ssbprize.gov.in/Content/AwardeeList.aspx | title=View Bhatnagar Awardees | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=19 September 2016}}</ref>

== Biography ==
Guru Prakash Dutta, after graduating in zoology in 1952 from DAV College, [[Jallandhar]]<ref name="Histochemical Studies of Herpetomonas muscarum">{{cite journal | url=http://jcs.biologists.org/content/joces/s3-100/51/413.full.pdf | title=Histochemical Studies of Herpetomonas muscarum | author=G. P. Dutta | journal=Journal of Microscopical Science | date=September 1959 | volume=100 | issue=3 | pages=413–419}}</ref> of [[Punjab University, Chandigarh, India|Punjab University]], followed it up with an honors degree in 1955, a master's degree (MSc) in 1956 and a doctoral degree (PhD) in 1961 from the same institution.<ref name="Indian Fellow - G. P. Dutta" /> He started his career as a lecturer at his alma mater in 1962 where he stayed till his move to [[Central Drug Research Institute]] (CDRI) in 1964; in between, he had a stint at [[National Institutes of Health]], Bethesda as a post-doctoral fellow during 1962–63. He served CDRI for more than three decades and was a director's grade scientist at the time of his superannuation in 1993. Post his retirement, he served as an emeritus scientist of the [[Council of Scientific and Industrial Research]] at CDRI from 1994 to 1998 and as an honorary consultant on [[Malaria]] at the [[Central Institute of Medicinal and Aromatic Plants]] from 1998 to 2000.<ref name="Indian Fellow - G. P. Dutta" />

Dutta, whose researches on experimental [[protozoology]] assisted in a wider understanding of [[protozoa]] and its functional [[Morphology (biology)|morphology]], is known to have developed new techniques for the culture of those unicellular [[eukaryotic]] organisms and studied their metabolic and growth responses to ''physico-chemical'' factors, with special emphasis on [[Entamoeba histolytica]], an [[Anaerobic organism|anaerobic]] parasite which causes [[amoebiasis]].<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=19 September 2016 | pages=36 | archive-url=https://web.archive.org/web/20160304043957/http://www.csirhrdg.res.in/ssb.pdf | archive-date=4 March 2016 | url-status=dead }}</ref> His work on the antimalarial drugs helped in the development of several fast-acting drugs and ''alpha/beta'' [[arteether]], ''alpha'' and ''beta'' [[arteether]], ''alpha'' and ''beta'' artelinate, [[dihydroartemisinin]], [[pyronaridine]], bulaquine and Tefenoquine are some of drugs developed with the assistance of his researches.<ref name="Indian Fellow - G. P. Dutta" />{{Refn|group=note|It is reported that 30 patents have been granted for drugs based on Dutta's researches.<ref name="Indian Fellow - G. P. Dutta" />}}

Dutta's researches have been detailed in over 275 articles<ref name="Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin">{{cite journal | title=Stereoselective Synthesis and Antimalarial Activity of α-Artelinic Acid from Artemisinin |author1=R. A. Vishwakarma |author2=R. Mehrotra |author3=R. Tripathi |author4=G. P. Dutta | journal=J. Nat. Prod. | year=1992 | volume=55 | issue=8 | pages=1142–1144 | doi=10.1021/np50086a018|pmid=1431937 }}</ref><ref name="Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo">{{cite journal | url=https://www.researchgate.net/publication/7018115 | title=Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo |author1=Renu Tripathi |author2=Charles W Jefford |author3=G P Dutta | journal=Parasitology | date=August 2006 | volume=133 | issue=1 | pages=1–9 | doi=10.1017/s0031182006009905| pmid=16764736 }}</ref> and two books, ''Antimalarial Drug Development and Prophylaxis against Malaria'' and ''Experimental and Clinical Studies on Amoebiasis''.<ref name="Experimental and Clinical Studies on Amoebiasis">{{cite book | title=Experimental and Clinical Studies on Amoebiasis | publisher=Tata-McGraw Hill | author=G. P. Dutta | year=1982 | pages=390 | isbn=978-0070963955}}</ref> The [[International Review of Cytology]] of [[Academic Press]] has published five reviews, three on [[Cytochemistry]] and ultrastructure of Protozoa and two on [[Amoebiasis]] and [[ResearchGate]], an online repository of scientific articles, has listed 130 of his papers.<ref name="G P Dutta on ResearchGate">{{cite web | url=https://www.researchgate.net/researcher/39654454_G_P_Dutta | title=G P Dutta on ResearchGate | work=Author search | date=2016 | access-date=21 September 2016}}</ref> He has been a collaborator for [[Walter Reed Army Institute of Research]] in two of their international programs on Malaria which ran between 1983 and 1994. He has also mentored 40 master's and doctoral scholars in their researches.<ref name="Indian Fellow - G. P. Dutta" />

Dutta received the degree of Doctor of Science from the [[Punjab University, Chandigarh, India|Punjab University]] in 1973 and the [[Council of Scientific and Industrial Research]] awarded him the [[Shanti Swarup Bhatnagar Prize]], one of the highest Indian science awards, for his contributions to biological sciences in 1976.<ref name="Brief Profile of the Awardee" /> The [[Indian National Science Academy]] elected him as their fellow in 1984 and the [[National Academy of Sciences, India]] followed INSA with their fellowship in 1991.<ref name="NASI fellows">{{cite web | url=http://www.nasi.org.in/fellows.asp?RsFilter=D | title=NASI fellows | publisher=National Academy of Sciences, India | date=2016 | access-date=22 September 2016}}</ref> He was also elected by the Indian Society for Parasitology as a fellow in 1993.<ref name="Fellows - ISP">{{cite web | url=http://www.parasitologyindia.org/fellows.htm | title=Fellows - ISP | publisher=Indian Society for Parasitology | date=2016 | access-date=21 September 2016 | archive-url=https://web.archive.org/web/20141213195132/http://www.parasitologyindia.org/fellows.htm | archive-date=13 December 2014 | url-status=dead | df=dmy-all }}</ref>

== See also ==
* [[Central Drug Research Institute]]
* [[Central Institute of Medicinal and Aromatic Plants]]
* [[Walter Reed Army Institute of Research]]

== Notes ==
{{Reflist|group=note}}

== References ==
{{Reflist|30em}}

{{SSBPST recipients in Biological Science}}

{{Authority control}}

{{DEFAULTSORT:Dutta, Guru Prakash}}
[[Category:1933 births]]
[[Category:2021 deaths]]
[[Category:Recipients of the Shanti Swarup Bhatnagar Award in Biological Science]]
[[Category:Indian cell biologists]]
[[Category:Indian immunologists]]
[[Category:Panjab University alumni]]
[[Category:National Institutes of Health people]]
[[Category:Indian medical writers]]
[[Category:Fellows of the Indian National Science Academy]]
[[Category:Fellows of The National Academy of Sciences, India]]
[[Category:Council of Scientific and Industrial Research]]
[[Category:20th-century Indian biologists]]
[[Category:Scientists from Punjab, India]]

Guru Prakash Dutta - Revision history

CleanupBot II at 22:13, 13 August 2023