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The 2022 Indiana State Sycamores football team represent Indiana State University as a member of the Missouri Valley Football Conference (MVFC) during the 2022 NCAA Division I FCS football season. They are led fifth-year head coach Curt Mallory. The Sycamores play their home games at Memorial Stadium in Terre Haute, Indiana.
Previous season
The Sycamores finished the 2021 season with a record of 5–6, 3–5 MVFC play to finish in a tie for seventh place.
Schedule
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