Ambani is a surname and may refer to the following people:
Some people of Ambani surname
- Anil Ambani, an Indian businessman and chairman of Reliance Group
- Dhirubhai Ambani, an Indian businessman and founder of Reliance Industries in Mumbai
- Mukesh Ambani, an Indian businessman and largest shareholder of Reliance Industries; one of the richest persons in India
- Nita Ambani, reportedly India's wealthiest woman, chairperson and founder of Reliance Foundation, founder of Dhirubhai Ambani International School (DAIS) and a non-executive director of Reliance Industries
- Tina Ambani, a former Indian actress and chairman of Reliance Anil Dhirubhai Ambani Group, founder of Kokilaben Dhirubhai Ambani Hospital (KDAH); actively involved in many foundations and charities