Bharat Biotech International Limited (BBIL) is an Indian multinational biotechnology company headquartered in Hyderabad, engaged in the drug discovery, drug development, manufacture of vaccines, bio-therapeutics, pharmaceuticals and health care products.[1]
Overview
Bharat Biotech has its manufacturing facility situated at Genome Valley, Hyderabad, India.[1] As of July 2020, the company has over 700 employees[2] and has a presence worldwide.[1]
The company has been responsible for developing an eco-friendly recombinant[3] and a naturally attenuated strain derived Rotavirus vaccine called ROTAVAC.[4][5] They were one of the first to develop vaccines for viral diseases like Chikungunya[6][7] and Zika.[8][9] The company also produces vaccines for Japanese Encephalitis.[10] Bharat Biotech has biosafety level 3 (BSL3) laboratories.[11]
COVID-19 vaccine development
In April 2020, the company announced that they have partnered with US-based company FluGen and University of Wisconsin-Madison to develop a COVID-19 vaccine.[12][13]
In May 2020, Indian Council of Medical Research's (ICMR's) National Institute of Virology approved and provided the virus strains for developing a fully indigenous COVID-19 vaccine.[14][15] On June 29, 2020, the company got permission to conduct Phase 1 and Phase 2 clinical trials in India for a developmental COVID-19 vaccine named Covaxin, from the Drugs Controller General of India (DCGI), Government of India.[16][17][18][19] The Central Drugs Laboratory (CDL) at Kasauli in Himachal Pradesh has been engaged in testing experimental batches of Bharat Biotech's COVID-19 vaccine Covaxin on a priority basis.[20] A total of 12 sites were selected by the Indian Council for Medical Research for Phase I and II randomised, double-blind and placebo-controlled clinical trials of vaccine candidate.[21][22]
In September 2020, the company announced that it was going to manufacture the novel chimp-adenovirus, a single dose intranasal vaccine (codenamed BBV154) for COVID-19 being developed in collaboration with the Washington University School of Medicine in St Louis, Missouri. It is currently undergoing clinical trials.[23][24]
Attempted data theft
In March 2021, Reuters reported that Chinese state-backed cyber-espionage group Red Apollo targeted Bharat Biotech's intellectual property for exfiltration.[25]
See also
References
- ↑ 1.0 1.1 1.2 Bharat Biotech International Ltd. www.bloomberg.com. Retrieved 3 July 2020.
- ↑ Leading Biotech Vaccine Manufacturers in India - Bharat Biotech. www.bharatbiotech.com. Retrieved 30 June 2020.
- ↑ Process for the preparation and purification of recombinant proteins. patents.google.com. US patent No US8956812B2(23 August 2004). Retrieved 30 June 2020.
- ↑ Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial. The Lancet({Template:Date).
- ↑ Rotavirus vaccines.. Indian Journal of Medical Microbiology({Template:Date).
- ↑ Bharat Biotech's Zika, Chikungunya vaccines to enter Phase II trials; focus now on private label market. Moneycontrol. Retrieved 30 June 2020.
- ↑ CEPI, 치쿤구니아 백신 개발 위해 국제백신연구소-바라트 바이오텍 컨소시엄에 최대 1410만달러 지원. CEPI, 치쿤구니아 백신 개발 위해 국제백신연구소-바라트 바이오텍 컨소시엄에 최대 1410만달러 지원 - 뉴스와이어(3 June 2020).
- ↑ Bharat Biotech gets breakthrough in developing Zika vaccine. The Economic Times(4 February 2016). Retrieved 30 June 2020.
- ↑ CEPI awards up to US$14.1million to consortium of IVI and Bharat Biotech to advance development of Chikungunya vaccine in collaboration with Ind-CEPI – IVI. www.ivi.int. International Vaccine Institute. Retrieved 30 June 2020.
- ↑ A Japanese Encephalitis Vaccine From India Induces Durable and Cross-protective Immunity Against Temporally and Spatially Wide-ranging Global Field Strains. Journal of Infectious Diseases({Template:Date).
- ↑ Slow off the starting blocks for Bharat Biotech's Covaxin mass production. The New Indian Express(17 May 2021). Retrieved 2021-06-04.
- ↑ UW-Madison, Flugen, Bharat Biotech to develop coroflu, a coronavirus vaccine. Global Health Institute. Retrieved 30 June 2020.
- ↑ Bharat Biotech ties up with US varsity for Covid vaccine. Hindustan Times(20 May 2020). Retrieved 30 June 2020.
- ↑ ICMR teams up with Bharat Biotech to develop Covid-19 vaccine. Livemint(9 May 2020). Retrieved 30 June 2020.
- ↑ India to develop 'fully indigenous' Covid vaccine as ICMR partners with Bharat Biotech. ThePrint(10 May 2020). Retrieved 30 June 2020.
- ↑ India's First COVID-19 Vaccine Candidate Approved for Human Trials. The New York Times(29 June 2020). Retrieved 30 June 2020.
- ↑ Human trial of India coronavirus vaccine announced. BBC News(30 June 2020). Retrieved 30 June 2020.
- ↑ Bharat Biotech's Covid vaccine 1st in India to get approval for human trials. The Indian Express(30 June 2020). Retrieved 30 June 2020.
- ↑ Covaxin: India's first COVID19 vaccine candidate from Bharat Biotech to begin human trials; check details. The Financial Express(30 June 2020). Retrieved 30 June 2020.
- ↑ Bharat Biotech COVID-19 vaccine: Testing underway at CDL-Kasauli, volunteer enrolment begins. Moneycontrol. Retrieved 10 July 2020.
- ↑ Human clinical trials of potential Covid-19 vaccine 'COVAXIN' started at AIIMS. DD News(25 July 2020). Retrieved 7 August 2020.
- ↑ Delhi: 30-year-old is first to get dose of trial drug Covaxin. The Indian Express(25 July 2020). Retrieved 7 August 2020.
- ↑ Bharat Biotech to make a billion doses of an intranasal adenovirus vaccine. The Indian Express(23 September 2020). Retrieved 23 September 2020.
- ↑ Bharat Biotech Partners With US University For Covid Intranasal Vaccine. NDTV.com. Retrieved 23 September 2020.
- ↑ Chinese hackers target Indian vaccine makers SII, Bharat Biotech, says security firm. Reuters(2021-03-01). Retrieved 2021-03-01.